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Figure 1 | Molecular Cytogenetics

Figure 1

From: Activation of the two microRNA clusters C19MC and miR-371-3 does not play prominent role in thyroid cancer

Figure 1

miR-372 was upregulated in 2 of 114 thyroid carcinomas. (A) Relative expression of miR-372 was quantified in 114 thyroid carcinoma samples of different types (PTC: papillary thyroid carcinoma, FTC: follicular thyroid carcinoma, ATC: anaplastic thyroid carcinoma, MTC: medullary thyroid carcinoma, OTC: oncocytic thyroid carcinoma). Expression is compared to three different normal thyroid tissues. The thyroid tissue showing the highest expression of miR-372 was used as calibrator. A thyroid adenoma with 19q13.4 rearrangement (S1016) served as a positive control of abundant miR-372 expression. The arrows indicate the samples that also appear in Figure 3 (from left to right: normal thyroid tissue, S1016, KS 99, KS 97, KS 61, KS 41, KS 82, KS 106, KS 100, KS 13). RQ: relative quantity (logarithmic scale). The lower panel shows histological sections of (B) case KS 13, a follicular variant of papillary thyroid carcinoma (PTC) and (C) case KS 100, an anaplastic thyroid carcinoma (ATC).

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Molecular Cytogenetics

ISSN: 1755-8166