ZAP70 expression in adult ALL patients. (a) ZAP70 RNA expression in adult ALL patients quantified by RT-qPCR. (b) ZAP70 expression in combined adult B-ALL and T-ALL patient cohorts. (c) ZAP70 expression in adult B-ALL patients classified into different cytogenetic groups. The cytogenetic group classified as others includes Burkitt lymphoma, hyperdiploid, hypodiploid, monosomy 7 and MLL/AFF1. In each panel, ZAP70 mRNA levels were normalised to GAPDH expression and then reported as a fold increase/decrease relative to ZAP70 expression in the Jurkat cell line (set as an arbitrary value of 1.0); n = number of patients.