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Table 1 Previously reported CML cases with five-way translocations and the present case

From: A novel five-way translocation t(7;11;9;22;9)(q22;q13;q34;q11.2;q34) involving Ph chromosome in a patient of chronic myeloid leukemia: a case report

Case no.

Age/Sex

Karyotype of five-way translocation

Reference no.

Treatment

Outcome

1

10/Male

t(4;18;13;9;22)(q12;q11.2;q14;q34;q11.2)

[1]

BSF

Died 81months

2

23/Male

t(9;22;15;19;10)

[2]

Not reported

Not reported

3

68/Not reported

t(3;4;9;11;22)

[3]

Not reported

Died in benign phase

4

64/Female

t(9;22;21;11;inv ins(12)(q15p12p13)(q34;q11;q22;q13;q15)

[4]

BSF/VCR and PSL/ADM, CPA and MTX

Died 33 months

5

63/Male

t(9;22;10;12;1)(q34;q11.2;q22;p12;p36.1)

[5]

DNR,VCR,AND and PSL

Died 34 months

6

68/Female

t(9;22;15;13;17)(q34;q11;q26;q14;q11)

[6]

Chemotherapy

Not reported

7

Not reported/Male

t(2;9;16;22;22)(q32;q34;q21;q11;q11)

[7]

Not reported

Not reported

8

32/Male

t(4;12;7;9;22)(q33?;q24;p13;q34;q11)

[8]

GLI

41 months

9

45/Female

t(1;4;5;9;22)(q42;p14;q31;q34;q11.2)

[9]

HU/GLI

62 months

10

58/Male

t(7;11;9;22;9)(q22;q13;q34;q11.2;q34)

The present case

GLI

44 months

  1. BSF:Busulphan, VCR:Vincristine, PSL: Prednisolone, ADM:Adriamycin, CPA:Cyclophosphamide, MTX:Methotrexate, DNR:Daunorubicin, GLI:Imatinib, HU:Hydroxyurea.