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Figure 3 | Molecular Cytogenetics

Figure 3

From: Meiotic errors followed by two parallel postzygotic trisomy rescue events are a frequent cause of constitutional segmental mosaicism

Figure 3

Short tandem repeat analysis on DNA of the patient and parents. A) Case 1 has three different alleles for marker D13S128 corresponding to two different paternal alleles and one maternal allele. B) At marker D13S129 case 1 has two identical paternal alleles and one maternal allele. This indicates the paternal origin of the duplication in chromosome 13 and suggests a cross-over occurred between the paternal chromosomes 13 followed by a meiosis II non-disjunction and an unequal sisterchromatid exchange. C: case, F: father, M: mother.

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Molecular Cytogenetics

ISSN: 1755-8166