Table 1 Examples of polymorphic inversions and the related genomic disorders reported to be caused as secondary rearrangements.
From: High rates of de novo 15q11q13 inversions in human spermatozoa
INVERSION | SIZE (Mb) | GENOMIC DISORDER/REARRANGEMENT | REFERENCE |
|---|---|---|---|
inv(3)(q29) | 1.9 | 3q29 microdeletion syndrome | [29] |
inv(5)(q35) | 1.3 | Sotos syndrome | [30] |
inv(7)(q11.23) | 1.8 | Williams-Beuren syndrome | [31] |
inv(8)(p23) | 4.7 | 8p23 microdeletion syndrome | [32] |
inv(15)(q11q13) | 4 | Angelman syndrome | [12] |
inv(15)(q13.3) | 2 | 15q13.3 deletion syndrome | [33] |
inv(17)(q12) | 1.5 | RCAD syndrome | [29] |
inv(17)(q21.31) | 0.9 | 17q21.21 deletion syndrome | [34] |