Table 2 Cases in which microarray analysis did not detect aberrations identified by chromosome analysis or FISH

3

47,XY,+12[3]/46,XY[16]/92,XXYY[1]

nuc ish(CCND1,IGH@)x2 [202/202]

0

Arr(1-22)x2,(XY)x1

nuc ish(CD82,ATM)x2[199/200]

0

nuc ish(pBR12,APAF1)x3 [5/200]

2.5

nuc ish(D13S319,LAMP1)x2[204/204]

0

nuc ish(TP53,ERBB2)x2[200/200]

0

4

46,XY,del(4)(p?15.2),del(11)(q21q23.3),add(14)(q32)[10]/46,XY[9]

nuc ish(ATMx1), (KAI1x2)[ 74/200]

37.0

del chr11:101900200-113746962 (11q22.2q23.2)

11.8 Mb

nuc ish(ATMx1),(KAI1x1)[8/200]

4.0

nuc ish(D13S319x1),(LAMP1x1)[31/235]

13.2

nuc ish(D13S319x1),(LAMP1x2) [110/235]

46.8

del chr13:48903923-49406099 (13q14.3q14.3)

502 kb

nuc ish(5'IGHVx1,3'IGHx1)[7/227]

3.1

nuc ish(5'IGHVx2,3'IGHx2)(5'IGHV sep 3'IGHx1)[35/227]

15.4

nuc ish(5'IGHVx1,3'IGHx2)(5'IGHV sep 3'IGHx1)[40/227]

17.6

nuc ish( (TP53,ERBB2)x2[250/250]

0

nuc ish(MYCx3)[ 116/200]

58.0

dup chr8:124436106-146015567 (8q21.13q24.3)

21.6 Mb

del chr4:16516563-30324345 (4p15.32p15.1)

13.8 Mb

del chr7:81021736-96580930 (7q21.11q21.3)

15.5 Mb

7

46,XY,t(14;19)(q32.3;q13.2)[9]/46,XY[11]

nuc ish(CD82,ATM)x2[199/200]

0

nuc ish(pBR12,APAF1)x2[199/200]

0

nuc ish(D13S319,LAMP1)x2[243/243]

0

nuc ish(CCND1,IGH@)x2[200/200]

0

nuc ish(TP53x1),17cen(x2)[10/202]

5.0

del chr14:105267349-106339477 (14q32.33q32.33)

170 kb

del chr22:21330008-21570697 (22q11.22q11.22)

241 kb

8

46,XY,del(11)(q14q23)[4]/48,XY,+4,+inv(?18)(q21q23)[3]/46,XY[13]

nuc ish(CD82x2),(ATMx1)[21/200]

10.5

nuc ish(Pbr12,APAF1)x2[ 199/200]

0

nuc ish(D13S319x1),(LAMP1x2)[90/201]

44.8

del chr13:47759453-49406099(13q14.2q14.3)

1.6 Mb

nuc ish(CCND1,IGH@)x2[200/200]

0

nuc ish(TP53,ERBB2)x2[199/200]

0

dup chr4:1-191273063

Trisomy

dup chr18:1-76117153

Trisomy

10

47,XY,+12[9]/46,XY[11]

nuc ish(D11Z1x2),(ATMx3)[ 11/229]

4.8

nuc ish(DDIT3)x3[126/226]

55.8

up chr12:74345-132349534

Trisomy

nuc ish(D13S319,LAMP1)x2[199/200]

0

nuc ish(CCND1,IGH@)x2[200/200]

0

nuc ish(TP53x1),17cen(x2)[11/213]

5.2

del chr22:21044595-21570697 (22q11.22q11.22)

526 kb

16

Previous Sideline: 47,XX,t(2;14)(p13;q32.1),+12[1]/46,XX[19]

nuc ish(pBR12,APAF1)x3[3/202]

1.5

Arr(1-22,X)x2

17

Previous Sideline: 45,XY,del(3)(q21q27),-8,del(8)(p10),add(?9) (p13),del(11)(q13q23),del(13)(q14q22),add(17)(p10)[1]/46,XY[30]

nuc ish(CD82x2),(ATMx1)[6/200]

3.0

del chr11:84811642-124583747 (11q14.1q24.2)

39.8 Mb

nuc ish(D13S319x1),(LAMP1x2)[44/243]

18.1

del chr13:46386690-57242066 (13q14.2q21.1)

10.9 Mb

nuc ish(D13S319x0),(LAMP1x1 or 2)[33/243]

13.6

nuc ish(TP53x1),(ERBB2x2) [17/200]

8.5

dup chr2:44073-60812692 (2p25.3p16.1)

60.8 Mb

del chr6:57972657-147822754 (6p11.2q24.3)

89.9 Mb

del chr9:9839207-27863525 (9p23p21.2)

18.0 Mb

18

46,XY,t(3;11)(q21;p15)[,der(5)del(5)(q13q31)t(5;15)(q31;q13),r(?7)(p22q?22),der(15)t(5;15),-21[6]/46,XY[13]

nuc ish(CD82,ATM)x2[200/200]

0

nuc ish(pBR12,APAF1)x2[200 of 200]

0

nuc ish(D13S319,LAMP1)x1[27/200]

13.5

nuc ish(D13S319x1),(LAMP1x2)[82/200]

41.0

nuc ish(CCND1,IGH@)x2[228/228]

0

nuc ish(TP53,ERBB2)x2[195/200]

2.5

del chr3:66524310-71438751 (3p14.1p14.1)

4.9 Mb

del chr5:67408207-67790791 (5q13.1q13.1)

382 kb

del chr5:76836011-180616147 (5q14.1q35.3)

104 Mb

del chr7:2327342-54294538 (7p22.3p11.2)

54.2 Mb

del chr7:81021736-96580930 (7q21.11q21.3)

15.6 Mb

del chr7:102955780-158788150 (7q22.1q36.3)

55.8 Mb

del chr21:41514980-46912065 (21q22.3q22.3)

5.4 Mb

24

46,XY[20]

nuc ish(D11Z1,ATM)x2[213/213]

0

nuc ish(DDIT3)x2[229/229]

0

nuc ish(D13S319,LAMP1)x1[15/203]

7.4

del chr13:48903923-49406099 (13q14.3q14.3)

502.2 kb

nuc ish(D13S319x1),(LAMP1x2)[155/203]

76.3

nuc ish(CCND1,IGH@)x2[223/223]

0

nuc ish(TP53x2),17cen(x2)[199/200]

0

25

N.D.

uc ish(D11Z1,ATM)x2[212/213]

0

Arr(1-22,X)x2

nuc ish(DDIT3)x2[204/204]

0

nuc ish(D13S319x1),(LAMP1x2)[13/217]

6.0

nuc ish(D13S319x0),(LAMP1x2)[30/217]

13.8

nuc ish(D13S319x0),(LAMP1x2)[30/217]

0

nuc ish(TP53x2),17cen(x2)[199/200]

0