Skip to main content

Table 1 Potential secondary structure of individual PATRR11 variants by free energy calculation

From: DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation

Type of PATRR11

Nucleotide bp (Accession No.)

Gds Kcal/mole

Gstru Kcal/mole

ΔG Kcal/mole

Translocation frequency

L-PATRR11

445(AF391129)

-392.5

-178.4

17.9

1.32 × 10-5

 

450(AB235178)

-397.5

-187.9

10.9

2.11 × 10-5a

SS-PATRR11

292(AB235183)

-259.8

-121.8

8.1

1.73 × 10-6

 

350(AB235180)

-314

-144.7

12.3

1.82 × 10-6a

 

386(AB235182)

-335.2

-147.3

20.3

1.71 × 10-6

AS-PATRR11

212(AF391128)

-195.6

-83.1

14.7

<4.05 × 10-8a

 

277(AB235187)

-247.9

-104.2

19.8

<1.67 × 10-7

 

483(AB235186)

-252.9

-99.95

26.5

<7.62 × 10-8

 

434(AB235190)

-380.1

-157.3

32.8

6.81 × 10-7

  1. a These values are the mean of 4 (450 bp L-PATRR11 allele), 2 (350 bp SS-PATRR11 allele), and 3 (212 bp AS-PATRR11 allele)samples.
Back to article page

Molecular Cytogenetics

ISSN: 1755-8166