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Table 2 Comparison of EGFR gene amplification and protein expression in 69 cases of gastric cancer

From: Assessment of ERBB2 and EGFR gene amplification and protein expression in gastric carcinoma by immunohistochemistry and fluorescence in situ hybridization

IHC score

IHC

n (%)

FISH

n (%)

χ2

P- value

0

33(47.8%)

49(71.0%)

  

1+

20(29.0%)

5(7.2%)*

17.016

0.000

2+

11(15.9%)

10(14.5%)

  

3+

5(7.3%)

5(7.2%)

  

Total positive cases

36(52.2%)

20(29.0%)

  
  1. * In comparison to FISH results from combined samples with scores of 2+ and 3+. IHC, immunohistochemistry; FISH, fluorescence in situ hybridization; n, number of positive samples.