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Table 1 Comparison of ERBB2 gene amplification and protein expression in 69 cases of gastric cancer

From: Assessment of ERBB2 and EGFR gene amplification and protein expression in gastric carcinoma by immunohistochemistry and fluorescence in situ hybridization

IHC score

IHC

n (%)

FISH

n (%)

χ2

P- value

0

40(57.9%)

55(82.7%)

  

1+

16(23.3%)

3(4.3%)*

12.461

0.000

2+

9(13.0%)

7(10.1%)

  

3+

4(5.8%)

4(5.8%)

  

Total positive cases

29(42.0%)

14(20.3%)

  
  1. * In comparison to FISH results from combined samples with scores of 2+ and 3+. IHC, immunohistochemistry; FISH, fluorescence in situ hybridization; n, number of positive samples.