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Table 1 Summary of array CGH analysis in 5080 cases

From: Clinical implementation of whole-genome array CGH as a first-tier test in 5080 pre and postnatal cases

   Cases with abnormal array CGH analysisa Total (N) Detection rate (%)
   Aneuploidy (N) Deletion (N) Duplication (N)   
Prenatal casesb (N = 4073)   60 7 8 75 1.8
Postnatal cases (N = 1007) PB with clinical indicationsc (N = 407) 5 19 10 34 8.3
  CB (N = 600) 0 4 1 5 0.83
Total 5080 65 30 19 114 2.24
  1. PB, Peripheral Blood; CB, Cord Blood for banking in general population
  2. aKaryotype and FISH analyses performed with array CGH anaysis. FISH analyses were performed using specific bacterial artificial chromosome (BAC) clones.
  3. bAF, Amniotic Fluid (N = 4033); CV, Chorionic Villi (N = 40)
  4. cClinical indications; developmental delay, mental retardation, dysmorphic feature, multiple congenital anomalies, etc.