Skip to main content
Figure 3 | Molecular Cytogenetics

Figure 3

From: A rare case of chronic myeloid leukemia with secondary chromosomal changes including partial trisomy 17q21 to 17qter and partial monosomy of 16p13.3

Figure 3

Karyotype and chromosomal aberrations were confirmed using molecular cytogenetic approaches. (A) M-FISH confirmed the complexity of the karyotype: 47,XY,t(9;22),der(16)t(16;17),+8. (B) and (C) The application of MCB 16 and 17 revealed the chromosomal breakpoints on the corresponding derivative chromosomes as 16p13.3 and 16 q22 and 17q21. (D) The deletion of the subtelomeric region on the der(16) and the translocation of chromosome 17 material was also demonstrated by the application of a subtelomeric probe for 16p (Abbott Molecular/Vysis, USA) and a whole chromosome painting (wcp) probe for chromosome 17.

Back to article page

Molecular Cytogenetics

ISSN: 1755-8166