Skip to main content
Figure 3 | Molecular Cytogenetics

Figure 3

From: Two siblings with immunodeficiency, facial abnormalities and chromosomal instability without mutation in DNMT3B gene but liability towards malignancy; a new chromatin disorder delineation?

Figure 3

Chromosome aberrations studied by Multiplex-FISH (M-FISH) method applying whole chromosome painting probes. Result is depicted in inverted DAPI-banding on the left and after M-FISH on the right. The near-triploid (hypotriploid) metaphase carried 60 chromosomes and multiple aberrations including fragmented chromatin belonging to chromosome 8 (= f(8)), dicentric chromosomes like a dic(14;14), a dic(15;15), and a dic(2;22), accompanied by acentric fragments (e.g. ace(15)).

Back to article page

Molecular Cytogenetics

ISSN: 1755-8166