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Table 1 Clinical data of patients and FISH results

From: No significantly increased frequency of the inversion polymorphism at the WBS-critical region 7q11.23 in German parents of patients with Williams-Beuren syndrome as compared to a population control

Samples Parameters for FISH analyses n With
inversion
With
inversion
%
P-value Female
carrier
Male
carriers
WBS parents II Couples with a WBS child 24 5 20.8   1* 5*
Control group I Couples with two healthy children 24 2 8.3 0.42 0 2
Control group II Couples with fertility problems, planning ICSI 16 4 25.0 1.00 1 3
Control group III Couples with two healthy children and one child with a
chromosome aberration (region 7q11.23 not involved)
11 1 9.1 0.64 1 0
Control groups (I-III)   51 7 13.7   2 5
       3 10
  1. *In one couple both of the father and the mother carried a paracentric inversion polymorphism at 7q11.23