Samples | Parameters for FISH analyses | n | With inversion | With inversion % | P-value | Female carrier | Male carriers |
---|---|---|---|---|---|---|---|
WBS parents II | Couples with a WBS child | 24 | 5 | 20.8 | 1* | 5* | |
Control group I | Couples with two healthy children | 24 | 2 | 8.3 | 0.42 | 0 | 2 |
Control group II | Couples with fertility problems, planning ICSI | 16 | 4 | 25.0 | 1.00 | 1 | 3 |
Control group III | Couples with two healthy children and one child with a chromosome aberration (region 7q11.23 not involved) | 11 | 1 | 9.1 | 0.64 | 1 | 0 |
Control groups (I-III) | 51 | 7 | 13.7 | 2 | 5 | ||
3 | 10 |