Figure 2From: MODY-like diabetes associated with an apparently balanced translocation: possible involvement of MPP7 gene and cell polarity in the pathogenesis of diabetes A. Sequences of PCR products from junctions aligned to reference human genome sequence. Upper case, chromosome 10 sequences. Lower case, chromosome 7 sequences. Upper case italics, origin unknown. B. UCSC Genome Browser tracks showing genes flanking the translocation breakpoints (arrows) and BAC clones used for FISH. C. FISH showing three signals for chromosome 7 (left) and chromosome 10 (right) BAC probes shown in B. D. Cartoon illustrating orientation of flanking genes and relative distances from translocation breakpoints.Back to article page