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Figure 6 | Molecular Cytogenetics

Figure 6

From: Meiotic and mitotic behaviour of a ring/deleted chromosome 22 in human embryos determined by preimplantation genetic diagnosis for a maternal carrier

Figure 6

Expected FISH signals in embryonic nuclei of balanced carriers and normal, non carriers, of the ring/deleted chromosome 22. No difference in the number of FISH signals can be detected in the first round. While in the second round four equal sized red signals are observed for the non-carrier, the carrier presents five signals three of which are of equal size and two that are smaller. The latter combination denotes the splitting of one of the signals for chromosome 22 and thus the existence of the deleted and ring chromosomes.

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