A) SubcenM-FISH revealed the absence of euchromatic material on the sSMCT reported here. The sSMCT only showed one specific signal, each, for midi 54 (a probe specific for the acrocentric short arms) and the centromeric probe specific for chromosome 14 and 22 (cep 14/22). No specific signals were on the sSMCT for the centromere-near probe RP11-324B11 in 14q11.2 and partial chromosome painting probe of chromosome 14 (the latter not depicted here). Thus, the sSMCT was a del(14)(q11.1). B) After knowing the origin of the sSMC array-CGH was reanalyzed for 14q-proximal region. The first probe on Agilent 4x44K array location is on 19,365,051-19,365,110 at 14q11.2. Thus, only genes from olfactory receptors OR11H12, OR4M1 and OR4Q3, and POTEG and P704P may be involved in the marker chromosome. As it is a region known to be CNV polymorphic and the probe RP11-324B11 at 19,886,099-19,886,646 is not present on the marker according to FISH array-CGH overall is to be considered as non-informative for this sSMC.