Figure 5From: Detailed analysis of X chromosome inactivation in a 49,XXXXX pentasomy HUMANDREC amplification of patient's DNA showing alleles 173, 179 and 199 (top). Amplification following digestion with methylation-sensitive endonucleases HhaI and HpaII (bottom) indicates preferential inactivation of X chromosomes carrying the 173 allele and lack of amplification of the 199 paternal allele.Back to article page