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Figure 4 | Molecular Cytogenetics

Figure 4

From: Chromosome territories, X;Y translocation and Premature Ovarian Failure: is there a relationship?

Figure 4

Chromosome territory analysis. FISH on interphase nuclei to detect reciprocal disposition of chromosome territories (line I and II). FISH was performed using WCPX (green in I/red in II) and WCPY (red in I/green in II). The images represent the three groups of chromosome territory disposition in the patient (I) and in male controls (II): distance smaller than 30% (A, D), distance between 30% and 50% (B, E) and distance more than 50% (C, F) of nuclear diameter. FISH on interphase nuclei to visualise centromere disposition of patient's sexual chromosome (line III) using CEPX (green) and CEPY (red) probes. The images represent the three disposition groups of centromeres (arrows) within the nucleus: signals positioned at a distance smaller than 30% (G), between 30% and 50% (H) and more than 50% (I) of nuclear diameter. Bar = 10 μm.

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