Cytogenetics analysis. Ideogram of X and Y chromosomes: arrows indicate the breakpoint position in Xq13.1 and Yq11.223. (A). Conventional cytogenetic analysis: pair of sex chromosomes Q-banded (B) and G-banded (C). R-banded metaphase spread from patient's lymphocytes after BrdU incorporation in late S-phase. The derivative Y chromosome (arrowed) shows late replication (D).