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Figure 2 | Molecular Cytogenetics

Figure 2

From: Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer

Figure 2

Chromosome 2 oligonucleotide array CGH plots. Chromosome 2 plots are shown for one representative non-metastatic (SQnon-Met) and one representative metastatic (LiverMet) tumor. The normalized log2 ratio is on the Y axis, and the chromosome bands are designated on the X axis. Copy number gains and losses are designated by the bars above or below a log2 ratio of 0, respectively. The shaded area reflects the magnitude of the gain or loss. The metastatic tumors show only the larger chromosome 2 deletion (bottom panel), whereas the non-metastatic tumors demonstrate clonal heterogeneity, with the both the smaller deletion, as well as low-level mosaicism for the larger deletion (top panel).

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Molecular Cytogenetics

ISSN: 1755-8166