Partial GTG-banded karyogram and ideograms. GTG-banded normal chromosomes 3 homologous (left) and normal chromosome 12 plus the der(12) (right) are showned. Ideograms of the normal chromosome 3, 12 and of the der(12) with the inv dup(3)(q26.31qter) segment translocated on 12pter are represented. The localization of subtelomeric probes 3qter (red) and 12pter (green) are signed in the ideograms. The breakpoint of 3q26.31 is represented by an arrow (→).