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Table 1 Cell distribution with aberration of PU.1 in the spleens of radiation-induced myeloid leukemia mice

From: Rapid and reliable diagnosis of murine myeloid leukemia (ML) by FISH of peripheral blood smear using probe of PU. 1, a candidate ML tumor suppressor

  

No of metaphase cells with

No of interphase cells with

 
  

2 PU.1 signals

1 PU.1 signal (1 deleted)

   

Mouse ID

Exposure

Both normal

1 trans -located

2 trans -located

1 normal

1 trans -located

2 PU.1 signals

1 PU.1 signal (1 deleted)

 

b007

Gamma

1

0

0

19

0

1

19

Mosaic

b021

Gamma

0

0

0

14

0

0

50

All G1R2

b154

Gamma

0

0

0

18

0

2

48

Mosaic

c090

Gamma

15

0

0

0

0

50

0

All normal

d040

Gamma

0

0

0

9

0

0

50

All G1R2

e036

Gamma

0

0

0

20

0

0

50

All G1R2

e127

Gamma

0

0

0

20

0

0

50

All G1R2

h060

Neutron

0

0

0

7

0

0

50

All G1R2

h061

Neutron

0

12

0

8

0

23

27

Mosaic

h070

Neutron

0

0

0

7

0

0

50

All G1R2

h121

Neutron

0

0

2

0

18

9

41

Mosaic

h124

Neutron

0

0

0

20

0

0

50

All G1R2

j018

Neutron

0

0

0

8

0

0

20+30*

All G1R2

  1. *Cells with 1 signal of PU.1 and 3 centromere signals