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Figure 2 | Molecular Cytogenetics

Figure 2

From: Further delineation of complex chromosomal rearrangements in fertile male using multicolor banding

Figure 2

shows MCB pattern of the cytogenetic result. It shows multicolor banding (MCB) applying probe-sets for chromosomes 1, 2 and 4 characterized the breakpoints as 1p31.1, 2q24.3 and 4q31.3. The corresponding results are shown here. For each chromosome depicted the MCB-pseudo-colors as well as the underlying fluorescence profiles are shown (for details of MCB evaluation see [22]. The first of the 5 columns shows which probe set was used (MCB 1, 2 or 4). The second column shows the normal chromosomes #1, #2 and #4. The arrowhead shows the breakpoint as present in the derivative sister-chromosomes. Third to fifth columns show the derivative chromosomes (der) 1, 2 and 4. MCB 1 stains parts of der(1) and der(4), MCB 2 parts of der(1) and der(2) and MCB 4 parts of der(2) and der(4). Parts not stained by the corresponding MCB probe-sets are pseudo-colored in gray. Overall, the complex chromosomal rearrangement was balanced, according to molecular cytogenetics.

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