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Figure 2 | Molecular Cytogenetics

Figure 2

From: Partial monosomy 7q34-qter and 21pter-q22.13 due to cryptic unbalanced translocation t(7;21) but not monosomy of the whole chromosome 21: a case report plus review of the literature

Figure 2

(A) GTG-banding appearance of chromosomes 7, note the similarity of banding patterns. (B) FISH with whole chromosome painting (WCP) probes for chromosomes 7 (green) and 21 (red) showed a translocation involving these chromosomes. (C) Multicolor banding (MCB) analysis of chromosome 21 revealed the translocation to be unbalanced due to the loss of 21pter-q22.13 (R110 signals correspond to q21-q22.2 chromosome 21 region; SpectrumOrange signals – q11.1-q21 chromosome 21 region; TexasRed signals – q21-q22.3 chromosome 21 region; Cyanine 5 signals – p-arm and centromeric region of chromosome 21).

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Molecular Cytogenetics

ISSN: 1755-8166