Figure 1

A) Result of microdissection and reverse painting of the here reported new case with an sSMC stainable only by DNA derived from itself. In the right lower edge: inverted DAPI for the sSMC. B) Reverse painting with the microdissection derived probe shown in Fig. 2A to the case with an sSMC stainable only by DNA derived from itself [14]. No specific green FISH-signal was obtained here; as a positive control for FISH a centromeric probe for chromosome 13/21 (Q-BIOgene) was applied in parallel (red signal). In the right lower edge: inverted DAPI for the sSMC.