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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: False-positives and false-negatives in non-invasive prenatal testing (NIPT): what can we learn from a meta-analyses on > 750,000 tests?

Fig. 1

All newborns with clinical abnormalities and the causes of their problems are schematically depicted. In A the causes are specified as chromosomal aberrations (chr.), monogenetic (monog.), multigenetic (multig.), teratogenic (teratog.), and idiopathic (unclear) causes; in B all causes are summarized to 100%. It can be clearly seen that prenatally a maximum of 10% of the cases with clinical abnormalities can be characterized by a clear genetic cause; according to this review not more than 5% of these aberrant cases can be accessed by NIPT (green label)

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Molecular Cytogenetics

ISSN: 1755-8166