Figure 2
From: Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines
Karyotype and confirmatory FISH analysis for unbalanced translocation. Unbalanced translocation between chromosome 8 and chromosome 17 [40,XY,der(17)t(8;17)(B2;E2)], that is indicated by arrow (A). FISH using WCP 8 (green) and WCP 17 (red) confirmed two green signals for normal chromosome 8, one normal red signal for normal chromosome 17 and one derivative chromosome 17 due to the unbalanced translocation between 8 and 17, which is painted by partial red and green (B). Unbalanced translocation between chromosome 1 and chromosome 8 [41,XY,+Y,der(1)t(1;8)(A1;D1), that is indicated by arrow (C). FISH using WCP 8 (green) confirmed two green signals for normal chromosome 8 and one derivative chromosome 1 due to the unbalanced translocation between 1 and 8, which is painted by green partially (D).s