Figure 5From: On the origin of trisomy 21 Down syndromeChanges in human oocyte number during prenatal and postnatal development. There is a very rapid increase in human female germ cell (oocyte) number early during fetal development with a peak at 7 months gestational age, followed by a relatively rapid decline before birth and postnatally before puberty, but a slower depletion during reproductive years until menopauseBack to article page